Kopfzentrum GruppePersonalized Regenerative Activation

Personalized Regenerative Activation

How can I purposefully stimulate my own cells to heal? 

The personalized activation of regeneration mechanisms is a new scientific approach in medicine. Natural messengers that are synthetically manufactured as medicines and delivered to the affected area can stimulate the restoration of healthy tissue. KOPFZENTRUM has extensive experience in the field of mucous membrane and skin regeneration.

  • KOPFZENTRUM is one of the most experienced providers worldwide for the targeted activation of endogenous stem cells. Conservative and surgical procedures are successfully combined with cellular / molecular medicine techniques.
  • By October 2017, more than 400 patients had been treated. The response rate of the therapy is averaged over all therapy variants over 75 %. The therapeutic effect usually occurs between the 3rd week and the 3rd month after treatment.
  • The PRMM procedures are predominantly done with a tiny puncture (via a thin needle) into the target area, in some cases in combination with an intravenous infusion, in selected cases in combination with a small operation to remove adipose tissue.
  • The therapy does not have to be repeated in order to achieve the intended effect. A repetition is possible in principle.
  • Particularly promising are the therapeutic results in diseases with degenerative components, d. H. with functional limitations of the tissue.
  • Especially good experiences are available for the chronic inflammation of the nasal mucosa (sinusitis, rhinitis). For this indication, PRMM is already part of the standard treatment.
  • Impressive results are also documented for the treatment of acute hearing loss, dizziness, M. Meniere, chronic pain, scars, wound healing disorders.
  • The therapy is only partially taken over by the health insurances, since large studies to prove the economic efficiency are to be expected only from the year 2020 onwards.
  • All treatments are permitted under the German Medicines Act and the Medical Devices Act for human use. There is no stem cell manipulation, but a stimulation of the own stem cells instead.
  • The procedures according to PRMM are also permissible in the status complete remission after tumor diseases. A growth-inhibiting / regulating effect on tumors could be demonstrated.
  • Therapeutic procedures are constantly monitored and developed by KOPFZENTRUM and the official supervisory authorities.

Applications Personalized Regenerative Medicine (as of October 2017)


REF A Regeneration factors to the local
Application, no activation required
+ + + 190,00 €
REF B Personalized regeneration factors for
local application and more targeted effect,
Activation with blood (components)
++ ++ ++ 265,00 €
REF B plus Personalized regeneration factors
for local use,
additional support of the therapy as
intravenous infusion **
+++ ++ +++ 690,00 €
REF C Stem cell transfer from abdominal fat (ASCT),
local and systemic support with
personalized regeneration factors
+++ +++++ +++ 990,00 €


* The costs are only valid in connection with interventions according to EBM or GOÄ.
** If necessary, the systemic therapy can be carried out in cooperation with the partners of KOPFZENTRUM. This results in additional costs.

Download Center

Personalized Regenerative Activation (PRMM)
Share via